What is



For adults with active non-radiographic axial spondyloarthritis with objective signs of inflammation in whom TNF blockers did not work well.

RINVOQ is a once-daily pill. See it in action.

How does RINVOQ work in the body?

With non-radiographic axial spondyloarthritis (nr-axSpA), your overactive immune system mainly attacks your spine and may cause inflammation that contributes to back pain and stiffness.

RINVOQ is a JAK (Janus kinase) inhibitor that regulates your overactive immune system to help stop the attack. It works inside your cells to block certain signals that are thought to be an underlying cause of nr-axSpA inflammation.

JAK Inhibitors for non-radiographic axial spondyloarthritis

Because JAK inhibitors like RINVOQ affect the immune system, they can lower the ability to fight infections and may cause other serious side effects. It’s important to talk to your healthcare provider about the possible side effects of prescription treatments. Learn more >

When is the right time to ask for RINVOQ?

If you’re still experiencing symptoms after treatment with a TNF blocker, RINVOQ may help.

to back down

Email or download the brochure to learn more about RINVOQ.

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RINVOQ® (upadacitinib) pill.

See the results of RINVOQ, a once-daily pill

RINVOQ can significantly relieve back pain and stiffness, and improve your ability to do everyday activities. Before you and your doctor make a treatment decision, read about the Use and Important Safety Information below.

Explore RINVOQ results and talk to your rheumatologist.