For adults with moderate to severe Crohn’s disease in whom TNF blockers did not work well

Want the latest on how RINVOQ can help you put Crohn’s in check?

RINVOQ is a once-daily pill approved for Crohn's

In clinical studies, RINVOQ helped people living with CD experience remission at 12 weeks and 1 year.

Plus, RINVOQ helped deliver:

RAPID SYMPTOM RELIEF, including less abdominal pain and fewer bowel movements in as early as 2 weeks


VISIBLY REDUCED DAMAGE of the intestinal lining*

*Based on endoscopy at 12 weeks and 1 year.


In another study, many people were in remission, even at ~2 years

In a less rigorous study at ~2 years, physicians and patients knew that RINVOQ was being used, which may have influenced results. Results measured in RINVOQ-treated patients who met clinical response at 12 weeks.


RINVOQ may cause serious side effects, including:

  • Serious Infections, Cancer and Immune System Problems, and Blood Clots.
  • Increased risk of death in people age 50+ with at least 1 heart disease risk factor.
  • Increased risk of major cardiovascular events, such as heart attack, stroke, or death in people age 50+ with at least 1 heart disease risk factor, especially in current or past smokers.
  • Serious allergic reactions. Do not take if allergic to RINVOQ or its ingredients.

Learn more about these and other serious side effects >

See full Important Safety Information below.

Get an inside look to see how RINVOQ works

Get RINVOQ treatment for as little as $0 a month

With the RINVOQ Complete Savings Card, eligible commercially insured patients may pay as little as $0 for their prescription. 

Quick poll

What’s most important to you when looking for a Crohn’s disease treatment?

RINVOQ works with your body to fight the inflammation that can lead to Crohn's symptoms. Excess inflammation can be caused by different proteins, such as Janus kinase (JAK), that are found naturally within your body. RINVOQ targets some JAK proteins to help reduce inflammation.

See how RINVOQ works

Talk to your gastro about treatment options that may be appropriate for you. RINVOQ is proven to deliver rapid symptom relief in as early as 2 weeks and lasting remission at 1 year.

See RINVOQ’s results

Ask your doctor about treatment options that can help you achieve steroid-free remission.

Understand the importance of treatment goals

Discuss your symptoms

Make sure you get the most out of your partnership with your gastroenterologist. Use our treatment discussion tool to have a more productive conversation at your appointment. 

Make an informed choice

It’s important to talk with your gastroenterologist and consider the benefits and risks of RINVOQ to choose the treatment that’s right for you.

Your story can help others

Have you or a loved one been prescribed RINVOQ for Crohn’s disease? Share your experience to help inform and inspire people like yourself. To participate:

email us at or

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Get started with personalized support

From helping to find possible ways to save on the cost of your prescription to answering questions about your condition, RINVOQ Complete gives you the support you need to start your prescribed RINVOQ treatment plan.

RINVOQ Complete Savings Card Terms and Conditions

Eligibility: Available to patients with commercial insurance coverage for RINVOQ® (upadacitinib) who meet eligibility criteria. This co-pay assistance program is not available to patients receiving prescription reimbursement under any federal, state, or government-funded insurance programs (for example, Medicare [including Part D], Medicare Advantage, Medigap, Medicaid, TRICARE, Department of Defense, or Veterans Affairs programs) or where prohibited by law. Offer subject to change or termination without notice. Restrictions, including monthly maximums, may apply. This is not health insurance. For full Terms and Conditions, visit or call 1.800.2RINVOQ for additional information. To learn about AbbVie’s privacy practices and your privacy choices, visit