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Important facts about Crohn’s disease
Crohn’s disease is part of a larger group of illnesses called inflammatory bowel diseases (IBD). Crohn’s disease is a chronic, or long-term, condition that causes inflammation in the gastrointestinal (GI) tract, also known as the digestive system.
Symptoms of Crohn’s disease can range from mild to severe and vary depending on the person and affected area(s) of the GI tract. And because Crohn’s is a progressive condition, it’s important to understand that symptoms may change or even get worse over time.
Though the exact causes of Crohn’s disease are not known, a few contributing factors have been identified, including a person’s immune system, genetics, and environmental factors.
of people living with Crohn’s have a family member with the disease.
Because Crohn’s is a progressive disease, it can get worse over time and may lead to further complications if inadequately treated. That’s why it’s important to team up with a gastroenterologist early on to recognize the signs and set treatment goals that include controlling inflammation as soon as possible.
That's great to hear. Our treatment discussion tool can help you work with your gastroenterologist to see if RINVOQ is right for you.
That's great to hear. Our treatment discussion tool can help you work with your gastroenterologist to see if RINVOQ is right for you.
That's great to hear. Our treatment discussion tool can help you work with your gastroenterologist to see if RINVOQ is right for you.
Many people living with Crohn’s disease keep experiencing flare-ups, which can occur between periods of remission. Unfortunately, these flare-ups are unpredictable, but you can manage them by working proactively with your gastroenterologist. To prepare for your visit, use our treatment discussion tool.
RINVOQ is a prescription medicine used to treat adults with moderate to severe Crohn’s disease when 1 or more medicines called tumor necrosis factor (TNF) blockers have been used, and did not work well or could not be tolerated. It is not known if RINVOQ is safe and effective in children with Crohn’s disease.
IMPORTANT SAFETY INFORMATION
What is the most important information I should know about RINVOQ?
RINVOQ may cause serious side effects, including:
Do not take RINVOQ if you are allergic to upadacitinib or any of the ingredients in RINVOQ. See the Medication Guide or Consumer Brief Summary for a complete list of ingredients.
What should I tell my HCP BEFORE starting RINVOQ?
Tell your HCP if you:
Tell your HCP about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. RINVOQ and other medicines may affect each other, causing side effects.
Especially tell your HCP if you take:
If you are not sure if you are taking any of these medicines, ask your HCP or pharmacist.
What should I avoid while taking RINVOQ?
Avoid food or drink containing grapefruit during treatment with RINVOQ as it may increase the risk of side effects.
What should I do or tell my HCP AFTER starting RINVOQ?
What are other possible side effects of RINVOQ?
Common side effects include upper respiratory tract infections (common cold, sinus infections), shingles (herpes zoster), herpes simplex virus infections (including cold sores), bronchitis, nausea, cough, fever, acne, headache, increased blood levels of creatine phosphokinase, allergic reactions, inflammation of hair follicles, stomach-area (abdominal) pain, increased weight, flu, tiredness, lower number of certain types of white blood cells (neutropenia, lymphopenia, leukopenia), muscle pain, flu-like illness, rash, increased blood cholesterol levels, increased liver enzyme levels, pneumonia, low number of red blood cells (anemia), and infection of the stomach and intestine (gastroenteritis).
A separation or tear to the lining of the back part of the eye (retinal detachment) has happened in people with atopic dermatitis treated with RINVOQ. Call your HCP right away if you have any sudden changes in your vision during treatment with RINVOQ.
Some people taking RINVOQ may see medicine residue (a whole tablet or tablet pieces) in their stool. If this happens, call your healthcare provider.
These are not all the possible side effects of RINVOQ.
How should I take RINVOQ?
RINVOQ is taken once a day with or without food. Do not split, crush, or chew the tablet. Take RINVOQ exactly as your HCP tells you to use it. RINVOQ is available in 15 mg, 30 mg, and 45 mg extended-release tablets.
This is the most important information to know about RINVOQ. For more information, talk to your HCP.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.
USES
RINVOQ is a prescription medicine used to treat:
It is not known if RINVOQ is safe and effective in children with juvenile idiopathic arthritis, psoriatic arthritis, ankylosing spondylitis, non-radiographic axial spondyloarthritis, ulcerative colitis, or Crohn’s disease.
RINVOQ is safe and effective in children 12 years of age and older weighing at least 88 pounds (40 kg) with atopic dermatitis.
It is not known if RINVOQ is safe and effective in children under 12 years of age with atopic dermatitis.
If you are having difficulty paying for your medicine, AbbVie may be able to help. Visit AbbVie.com/myAbbVieAssist to learn more.
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Please see the Full Prescribing Information, including the Medication Guide, for RINVOQ.
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