with a gastroenterologist
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CallWarning: Serious Infections, Increased Risk of Death, Cancer, Major Cardiovascular Events, Blood Clots
For adults with moderate to severe Crohn’s disease in whom TNF blockers did not work well
with a gastroenterologist
You play an important role in this partnership. The testing your gastroenterologist performs only tells part of the story. Your personal experience with Crohn’s disease tells the rest of it. That’s why having a voice and speaking up during your gastroenterologist visit matters.
Brushing up on Crohn’s disease terminology can make your next visit more productive. It is easy to get started with our glossary.
An important goal in treating Crohn’s disease is a visible reduction in damage of the intestinal lining sometimes called endoscopic improvement. Remember, intestinal lining damage can still be present even if you don’t have Crohn’s symptoms. Talk to your doctor about endoscopic improvement.
If you’ve ever taken a TNF blocker such as HUMIRA® or REMICADE® to treat moderate to severe Crohn’s disease, RINVOQ is a once-daily pill that may be another option for you.
RINVOQ is proven to help deliver rapid symptom relief, visibly reduced intestinal lining damage, and a chance to be in early remission without steroids.
RINVOQ is not for everyone. Before you and your doctor make a treatment decision, read about the Use and Important Safety Information below. Working together with your doctor can help you determine if RINVOQ is right for you.
REMICADE® (infliximab) is a registered trademark of Janssen Biotech, Inc.
RINVOQ is a prescription medicine used to treat adults with moderate to severe Crohn’s disease when 1 or more medicines called tumor necrosis factor (TNF) blockers have been used, and did not work well or could not be tolerated. It is not known if RINVOQ is safe and effective in children with Crohn’s disease.
IMPORTANT SAFETY INFORMATION
What is the most important information I should know about RINVOQ?
RINVOQ may cause serious side effects, including:
Do not take RINVOQ if you are allergic to upadacitinib or any of the ingredients in RINVOQ. See the Medication Guide or Consumer Brief Summary for a complete list of ingredients.
What should I tell my HCP BEFORE starting RINVOQ?
Tell your HCP if you:
Tell your HCP about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. RINVOQ and other medicines may affect each other, causing side effects.
Especially tell your HCP if you take:
If you are not sure if you are taking any of these medicines, ask your HCP or pharmacist.
What should I avoid while taking RINVOQ?
Avoid food or drink containing grapefruit during treatment with RINVOQ as it may increase the risk of side effects.
What should I do or tell my HCP AFTER starting RINVOQ?
What are other possible side effects of RINVOQ?
Common side effects include upper respiratory tract infections (common cold, sinus infections), shingles (herpes zoster), herpes simplex virus infections (including cold sores), bronchitis, nausea, cough, fever, acne, headache, increased blood levels of creatine phosphokinase, allergic reactions, inflammation of hair follicles, stomach-area (abdominal) pain, increased weight, flu, tiredness, lower number of certain types of white blood cells (neutropenia, lymphopenia, leukopenia), muscle pain, flu-like illness, rash, increased blood cholesterol levels, increased liver enzyme levels, pneumonia, low number of red blood cells (anemia), and infection of the stomach and intestine (gastroenteritis).
A separation or tear to the lining of the back part of the eye (retinal detachment) has happened in people with atopic dermatitis treated with RINVOQ. Call your HCP right away if you have any sudden changes in your vision during treatment with RINVOQ.
Some people taking RINVOQ may see medicine residue (a whole tablet or tablet pieces) in their stool. If this happens, call your healthcare provider.
These are not all the possible side effects of RINVOQ.
How should I take RINVOQ?
RINVOQ is taken once a day with or without food. Do not split, crush, or chew the tablet. Take RINVOQ exactly as your HCP tells you to use it. RINVOQ is available in 15 mg, 30 mg, and 45 mg extended-release tablets.
This is the most important information to know about RINVOQ. For more information, talk to your HCP.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.
USES
RINVOQ is a prescription medicine used to treat:
It is not known if RINVOQ is safe and effective in children with juvenile idiopathic arthritis, psoriatic arthritis, ankylosing spondylitis, non-radiographic axial spondyloarthritis, ulcerative colitis, or Crohn's disease.
RINVOQ is safe and effective in children 12 years of age and older weighing at least 88 pounds (40 kg) with atopic dermatitis.
It is not known if RINVOQ is safe and effective in children under 12 years of age with atopic dermatitis.
If you are having difficulty paying for your medicine, AbbVie may be able to help. Visit AbbVie.com/myAbbVieAssist to learn more.
US-RNQ-220259
Please see the Full Prescribing Information, including the Medication Guide, for RINVOQ.
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