For adults with moderate to severe rheumatoid arthritis (RA) in whom TNF blockers did not work well.

What is RINVOQ? (upadacitinib) 15mg tablets

RINVOQ? (upadacitinib) 15mg tablets

What is RINVOQ? (upadacitinib) 15mg tablets

Rethink what’s possible

If your TNF blocker treatment isn’t helping you meet your goals, and you’re still experiencing symptoms, see how RINVOQ is different. RINVOQ is a JAK inhibitor

RINVOQ is a once-daily pill for adults with moderate to severe RA that can tame joint pain, swelling and stiffness, stop irreversible joint damage, and significantly reduce RA fatigue.

The science behind RINVOQ

With RA, your overactive immune system attacks your joints. RINVOQ is a JAK (Janus kinase) inhibitor that regulates your overactive immune system to help stop the attack. RINVOQ works inside your cells to block certain signals that are thought to cause inflammation.

JAK Inhibitors for rheumatoid arthritis

Because JAK inhibitors, including RINVOQ, affect the immune system, they can lower the ability to fight infections and may cause other serious side effects. It’s important to talk to your healthcare provider about the possible side effects of prescription treatments.

Get an inside look at how RINVOQ works

HUMIRA® is a registered trademark of AbbVie Inc. ENBREL® (etanercept) is a registered trademark of Immunex Corporation in the US.

A once-daily pill, not an injection, to treat rheumatoid arthritis

Illustration of clock symbolizing how often to take RINVOQ

Take RINVOQ once a day, every day

Illustration of a fork and a knife crossing

RINVOQ can be taken with or without food

Avoid food or drink containing grapefruit

An illustration of a pill being split with a no symbol over it

Do not split, crush, or chew the pill

RINVOQ pill next to a glass of water

Call your healthcare provider if you see medication residue (a whole tablet or tablet pieces) in your stool.

Arthritis Foundation Ease of Use

A bottle designed with patients in mind

  • Awarded the Arthritis Foundation’s Ease of Use Commendation
  • Innovative bottle cap
  • Wide profile and easy-grip texture
  • Embedded tool seamlessly punctures the foil liner

Could RINVOQ be right for you?

If you have moderate to severe RA and you’re still experiencing symptoms after a TNF blocker, it may be time to talk to your rheumatologist about a different treatment option. See the results > 

What's most important to you when it comes to your RA treatment?

What's most important to you when it comes to your RA treatment?

See RINVOQ results
Now that you understand how RINVOQ works, take a closer look at results from clinical studies.

Is it time to evaluate your treatment plan?

Deciding to change your treatment is never easy, but neither is living with RA symptoms. 

Meet people who were still experiencing RA symptoms and worked with their rheumatologist to find a treatment option that worked for them.