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For adults with moderate to severe rheumatoid arthritis (RA) in whom TNF blockers did not work well.
If your TNF blocker treatment isn’t helping you meet your goals, and you’re still experiencing symptoms, see how RINVOQ is different. RINVOQ is a JAK inhibitor.
RINVOQ is a once-daily pill for adults with moderate to severe RA that can tame joint pain, swelling and stiffness, stop irreversible joint damage, and significantly reduce RA fatigue.
With RA, your overactive immune system attacks your joints. RINVOQ is a JAK (Janus kinase) inhibitor that regulates your overactive immune system to help stop the attack. RINVOQ works inside your cells to block certain signals that are thought to cause inflammation.
Because JAK inhibitors, including RINVOQ, affect the immune system, they can lower the ability to fight infections and may cause other serious side effects. It’s important to talk to your healthcare provider about the possible side effects of prescription treatments.
No, I have not been prescribed a TNF blocker
Finding an RA treatment that’s right for you takes assessing your symptoms, setting goals, and working with a rheumatologist to develop a treatment plan.
HUMIRA® is a registered trademark of AbbVie Inc. ENBREL® (etanercept) is a registered trademark of Immunex Corporation in the US.
Take RINVOQ once a day, every day
RINVOQ can be taken with or without food
Avoid food or drink containing grapefruit
Do not split, crush, or chew the pill
Call your healthcare provider if you see medication residue (a whole tablet or tablet pieces) in your stool.
If you have moderate to severe RA and you’re still experiencing symptoms after a TNF blocker, it may be time to talk to your rheumatologist about a different treatment option. See the results >
What's most important to you when it comes to your RA treatment?
What's most important to you when it comes to your RA treatment?
This is how others answered:
See RINVOQ results
Now that you understand how RINVOQ works, take a closer look at results from clinical studies.
RINVOQ is a prescription medicine used to treat adults with moderate to severe rheumatoid arthritis when 1 or more medicines called tumor necrosis factor (TNF) blockers have been used, and did not work well or could not be tolerated. It is not known if RINVOQ is safe and effective in children with juvenile idiopathic arthritis.
IMPORTANT SAFETY INFORMATION
What is the most important information I should know about RINVOQ?
RINVOQ may cause serious side effects, including:
Do not take RINVOQ if you are allergic to upadacitinib or any of the ingredients in RINVOQ. See the Medication Guide or Consumer Brief Summary for a complete list of ingredients.
What should I tell my HCP BEFORE starting RINVOQ?
Tell your HCP if you:
Tell your HCP about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. RINVOQ and other medicines may affect each other, causing side effects.
Especially tell your HCP if you take:
If you are not sure if you are taking any of these medicines, ask your HCP or pharmacist.
What should I avoid while taking RINVOQ?
Avoid food or drink containing grapefruit during treatment with RINVOQ as it may increase the risk of side effects.
What should I do or tell my HCP AFTER starting RINVOQ?
What are other possible side effects of RINVOQ?
Common side effects include upper respiratory tract infections (common cold, sinus infections), shingles (herpes zoster), herpes simplex virus infections (including cold sores), bronchitis, nausea, cough, fever, acne, headache, increased blood levels of creatine phosphokinase, allergic reactions, inflammation of hair follicles, stomach-area (abdominal) pain, increased weight, flu, tiredness, lower number of certain types of white blood cells (neutropenia, lymphopenia, leukopenia), muscle pain, flu-like illness, rash, increased blood cholesterol levels, increased liver enzyme levels, pneumonia, low number of red blood cells (anemia), and infection of the stomach and intestine (gastroenteritis).
A separation or tear to the lining of the back part of the eye (retinal detachment) has happened in people with atopic dermatitis treated with RINVOQ. Call your HCP right away if you have any sudden changes in your vision during treatment with RINVOQ.
Some people taking RINVOQ may see medicine residue (a whole tablet or tablet pieces) in their stool. If this happens, call your healthcare provider.
These are not all the possible side effects of RINVOQ.
How should I take RINVOQ?
RINVOQ is taken once a day with or without food. Do not split, crush, or chew the tablet. Take RINVOQ exactly as your HCP tells you to use it. RINVOQ is available in 15 mg, 30 mg, and 45 mg extended-release tablets.
This is the most important information to know about RINVOQ. For more information, talk to your HCP.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.
USES
RINVOQ is a prescription medicine used to treat:
It is not known if RINVOQ is safe and effective in children with juvenile idiopathic arthritis, psoriatic arthritis, ankylosing spondylitis, non-radiographic axial spondyloarthritis, ulcerative colitis, or Crohn’s disease.
RINVOQ is safe and effective in children 12 years of age and older weighing at least 88 pounds (40 kg) with atopic dermatitis.
It is not known if RINVOQ is safe and effective in children under 12 years of age with atopic dermatitis.
If you are having difficulty paying for your medicine, AbbVie may be able to help. Visit AbbVie.com/myAbbVieAssist to learn more.
US-RNQ-220259
Please see the Full Prescribing Information, including the Medication Guide, for RINVOQ.
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