Music track throughout.
TEXT ON SCREEN: YOUR OVERACTIVE IMMUNE SYSTEM
ANNOUNCER VOICE OVER (AVO): With ankylosing spondylitis, or AS, your overactive immune system...
TEXT ON SCREEN: ATTACKS SPINAL JOINTS
AVO: ...attacks mainly spinal joints and may cause inflammation that contributes to other symptoms throughout your body, such as in the hips, neck, and shoulders.
TEXT ON SCREEN: RINVOQ® (upadacitinib)
RINVOQ is a prescription medicine used to treat adults with active ankylosing spondylitis when 1 or more medicines called tumor necrosis factor (TNF) blockers have been used, and did not work well or could not be tolerated. It is not known if RINVOQ is safe and effective in children with ankylosing spondylitis.
Please see Important Safety Information in video and on this web page. Please see link for the full Prescribing Information, including the Medication Guide.
AVO: That's where RINVOQ comes in. RINVOQ is a prescription medicine for adults with active ankylosing spondylitis (AS) in whom TNF blockers did not work well.
TEXT ON SCREEN: GET AN INSIDE LOOK AT HOW IT WORKS
AVO: Let's take a deeper, inside look at how it works in your body.
TEXT ON SCREEN: For illustrative purposes only
AVO: RINVOQ is a JAK inhibitor that works inside your cells to block certain signals that are thought to cause inflammation.
TEXT ON SCREEN: RINVOQ® (upadacitinib)
REGULATES & HELPS STOP
AVO: RINVOQ regulates your overactive immune system to help stop the attack.
TEXT ON SCREEN: RINVOQ CAN SIGNIFICANTLY RELIEVE AS
AVO: A clinical study has proven RINVOQ helps relieve AS...
TEXT ON SCREEN: RINVOQ HELPS RELIEVE AS BACK PAIN & STIFFNESS
AVO: ...back pain and stiffness.
TEXT ON SCREEN: RINVOQ® (upadacitinib)
ASK YOUR RHEUMATOLOGIST ABOUT RINVOQ RELIEF
AVO: That's RINVOQ relief
TEXT ON SCREEN: SAFETY CONSIDERATIONS
TEXT ON SCREEN: RINVOQ can lower your ability to fight infections, including TB. Serious infections and blood clots, some fatal;
TEXT ON SCREEN: Do not start RINVOQ if you have an infection. Before and during treatment your doctor will test for tuberculosis (TB) and do bloodwork. Please see additional Important Safety Information on this page.
AVO: RINVOQ can lower your ability to fight infections, including TB. Serious infections and blood clots, some fatal;...
TEXT ON SCREEN: cancers, including lymphoma and skin cancer; death, heart attack, stroke, and tears in the stomach or intestines occurred.
TEXT ON SCREEN: Tell your doctor if you have a history of these events, any infections, hepatitis B or C, or smoking.
Please see additional Important Safety Information on this page.
AVO: ...cancers, including lymphoma and skin cancer; death, heart attack, stroke, and tears in the stomach or intestines occurred.
TEXT ON SCREEN: People 50 and older with at least 1 heart disease risk factor have higher risks.
TEXT ON SCREEN: People 50 and older with at least 1 heart disease risk factor are at increased risk for death, heart attack, stroke and blood clots.
Please see additional Important Safety Information on this page.
AVO: People 50 and older with at least one heart disease risk factor have higher risks.
TEXT ON SCREEN: Don't take if allergic to RINVOQ as serious reactions can occur. Tell your doctor if you are or may become pregnant.
TEXT ON SCREEN: Get help if you have rash (hives), trouble breathing, feel faint or dizzy, have swelling of your lips, tongue, or throat.
Please see additional Important Safety Information on this page.
AVO: Don't take if allergic to RINVOQ as serious reactions can occur. Tell your doctor if you are or may become pregnant.
