RINVOQ is a JAK inhibitor for adults with active ankylosing spondylitis (AS) in whom TNF blockers did not work well.

Rebel Against.

ANKYLOSING
SPONDYLITIS (AS)

If you’re still experiencing AS symptoms after a TNF blocker like HUMIRA® or ENBREL®*, RINVOQ is different and may help.

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Powerful relief from AS back pain and stiffness.

In a clinical study, RINVOQ helped:

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Many people achieve significant relief from AS symptoms in 14 weeks vs placebo (44.5% vs 18.2%). Some saw improvement as fast as 4 weeks.

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Improve quality of life for AS patients.

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Increase functional mobility, making it easier to do everyday activities.

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Give people nights with less back pain for better days ahead.

Person stretching icon.

Increase functional mobility, making it easier to do everyday activities.

Person in bed icon.

Give people nights with less back pain for better days ahead.

QUESTION FOR YOU

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What best describes the status of your AS?

Pick one

Diagnosed and taking an NSAID (like aspirin or ibuprofen)

It may be time to talk to your rheumatologist about whether your current treatment is helping you get relief. Use a customized checklist to help you prepare for the conversation.

Start the Appointment Checklist

Diagnosed and on a biologic (injection or infusion) or oral small molecule

Prepare to talk treatment options and goals at your next rheumatologist visit—and ask about RINVOQ.

Start the Appointment Checklist

Not diagnosed

It’s time to get honest about your symptoms with a rheumatologist—a doctor who specializes in diseases like AS.

Partner with a rheumatologist

QUESTION FOR YOU

What best describes the status of your AS?

Pick one

Diagnosed and taking an NSAID (like aspirin or ibuprofen)

It may be time to talk to your rheumatologist about whether your current treatment is helping you get relief. Use a customized checklist to help you prepare for the conversation.

Start the Appointment Checklist

Diagnosed and on a biologic (injection or infusion) or oral small molecule

Prepare to talk treatment options and goals at your next rheumatologist visit—and ask about RINVOQ.

Start the Appointment Checklist

Not diagnosed

It’s time to get honest about your symptoms with a rheumatologist—a doctor who specializes in diseases like AS.

Partner with a rheumatologist

In a clinical study, RINVOQ helped:

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as many people experience significant improvement in their AS symptoms, like back pain and stiffness, vs placebo (45% vs 18%) at 14 weeks.

It's here: RINVOQ relief for AS in a once-daily pill

Control AS disease activity which is measured by a range of symptoms including: back pain, joint pain and swelling, enthesitis (pain and swelling in areas like the heel and elbow), fatigue, and morning stiffness.

Improve functional mobility making it easier to do everyday activities.

RINVOQ (upadacitinib) pill.

RINVOQ is a once-daily pill, not an injection.

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Understanding the possible side effects of RINVOQ

Consider the benefits and risks of taking RINVOQ to make an informed treatment choice with your rheumatologist.

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Jump start the conversation

Show up prepared for your next rheumatologist visit.

Challenge your expectations.
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You could pay as little as $5 a month

The RINVOQ Complete Savings Card may help eligible, commercially insured patients pay as little as $5 a month for RINVOQ.

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Share your RINVOQ story

Share your experience with RINVOQ to help inform and inspire others. To participate, please email us at

or call

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Find a rheumatologist near you

Partner with a doctor who specializes in diseases like AS and ask if RINVOQ could help you.

*ENBREL® (etanercept) is a registered trademark of Immunex Corporation.