Rebel Against.

ANKYLOSING
SPONDYLITIS (AS)

If you’re still experiencing AS symptoms after a TNF blocker like HUMIRA® or ENBREL®, RINVOQ is different and may help.

Sign up for more info

For adults with active ankylosing spondylitis (AS) in whom TNF blockers did not work well.

Powerful relief from AS back pain and stiffness.

In a clinical study, RINVOQ helped:

Calendar icon.

Many people achieve significant relief from AS symptoms in 14 weeks vs placebo (44.5% vs 18.2%). Some saw improvement as fast as 4 weeks.

Sun icon.

Improve AS quality of life for patients.

Person stretching icon.

Increase functional mobility, making it easier to do everyday activities.

Person in bed icon.

Give people nights with less back pain for better days ahead.

Person stretching icon.

Increase functional mobility, making it easier to do everyday activities.

Person in bed icon.

Give people nights with less back pain for better days ahead.

Select Important Safety Information

RINVOQ may cause serious side effects, including:

  • Serious Infections, Cancer and Immune System Problems, and Blood Clots.
  • Increased risk of death in people age 50+ with at least 1 heart disease risk factor.
  • Increased risk of major cardiovascular events, such as heart attack, stroke, or death in people age 50+ with at least 1 heart disease risk factor, especially in current or past smokers.
  • Serious allergic reactions. Do not take if allergic to RINVOQ or its ingredients.

Learn more about these and other serious side effects > See full Important Safety Information below.

QUESTION FOR YOU

What best describes the status of your AS?

Pick one

Diagnosed and taking an NSAID (like aspirin or ibuprofen)

It may be time to talk to your rheumatologist about whether your current treatment is helping you get relief. Use a customized checklist to help you prepare for the conversation.

Start the Appointment Checklist

Diagnosed and on a biologic (injection or infusion) or oral small molecule

Prepare to talk treatment options and goals at your next rheumatologist visit—and ask about RINVOQ.

Start the Appointment Checklist

Not diagnosed

It’s time to get honest about your symptoms with a rheumatologist—a doctor who specializes in diseases like AS.

Partner with a rheumatologist

In a clinical study, RINVOQ helped:

Understanding side effects icon.

as many people experience significant improvement in their AS symptoms, like back pain and stiffness, vs placebo (45% vs 18%) at 14 weeks.

It's here: RINVOQ relief for AS in a once-daily pill

Control AS disease activity which is measured by a range of symptoms including: back pain, joint pain and swelling, enthesitis (pain and swelling in areas like the heel and elbow), fatigue, and morning stiffness.

Improve functional mobility making it easier to do everyday activities.

RINVOQ (upadacitinib) pill.

RINVOQ is a once-daily pill, not an injection.

Woman talking with her doctor.

Jump start the conversation

Show up prepared for your next rheumatologist visit.

QUESTION FOR YOU

Check mark icon.

What best describes the status of your AS?

Pick one

Diagnosed and taking an NSAID (like aspirin or ibuprofen)

It may be time to talk to your rheumatologist about whether your current treatment is helping you get relief. Use a customized checklist to help you prepare for the conversation.

Start the Appointment Checklist

Diagnosed and on a biologic (injection or infusion) or oral small molecule

If ankylosing spondylitis (AS) symptoms are getting in the way of what’s meaningful to you, it’s time to talk to your rheumatologist about making a change.

Learn to set treatment goals

Not diagnosed

It’s time to get honest about your symptoms with a rheumatologist—a doctor who specializes in diseases like AS.

Partner with a rheumatologist

Challenge your expectations.
Dollar icon.

You could pay as little as $5 a month

The RINVOQ Complete Savings Card may help eligible, commercially insured patients pay as little as $5 a month for RINVOQ.

Man riding a scooter.
Book icon.

Share your RINVOQ story

Share your experience with RINVOQ to help inform and inspire others. To participate, please email us at

or call

.

Knowledge is

Learn more about RINVOQ and if it could be right for you. Use the brochure to guide the conversation with your rheumatologist at your next appointment.

ENBREL® (etanercept) is a registered trademark of Immunex Corporation.

Eligibility: Available to patients with commercial insurance coverage for RINVOQ® (upadacitinib) who meet eligibility criteria. This co-pay assistance program is not available to patients receiving prescription reimbursement under any federal, state, or government-funded insurance programs (for example, Medicare [including Part D], Medicare Advantage, Medigap, Medicaid, TRICARE, Department of Defense, or Veterans Affairs programs) or where prohibited by law. Offer subject to change or termination without notice. Restrictions, including monthly maximums, may apply. This is not health insurance. For full Terms and Conditions, visit RINVOQSavingsCard.com or call 1.800.2RINVOQ for additional information. To learn about AbbVie’s privacy practices and your privacy choices, visit https://privacy.abbvie