See what RINVOQ relief really means

The power of RINVOQ is here. A once-daily pill to help you push back on ankylosing spondylitis (AS).

In a clinical study, RINVOQ helped achieve powerful relief from back pain and stiffness

as many people on
RINVOQ experienced significant improvement

in their overall AS symptoms vs placebo
(44.5% vs 18.2%) at 14 weeks.

  • Treatment with RINVOQ helped decrease overall disease activity, relieve total back pain, reduce the length and severity of morning stiffness, and provide meaningful improvement in people’s ability to do everyday activities.
  • RINVOQ also helped reduce nocturnal pain, giving people nights with less back pain.
RINVOQ® (upadacitinib) pill.

Helps deliver fast relief

RINVOQ worked as quickly as 4 weeks for some people to help relieve AS symptoms. Many people significantly improved their overall AS symptoms at 14 weeks vs placebo (44.5% vs 18.2%).

Individual results may vary.

Understanding side effects icon.

Understanding the possible side effects of RINVOQ

Consider the benefits and risks of taking RINVOQ to make an informed treatment choice with your rheumatologist.

A man attending tele-appointment with his doctor.

In a clinical study, RINVOQ helped:

AS back pain and stiffness. It also made it easier for patients to do everyday activities.

overall AS disease activity, which was measured using a questionnaire about a range of symptoms including: back pain, joint pain and swelling, enthesitis (pain and swelling in areas like the heel and elbow), fatigue, and morning stiffness.

quality of life in AS patients.*

*Based on ASQoL—an 18-item questionnaire to measure the impact of AS disease on health-related quality of living including daily and social activities.

Increased physical function

RINVOQ helped make it easier to do everyday tasks. People on RINVOQ completed a questionnaire that asked about their ability to perform activities, such as:

Bent over person icon.

Bending at the waist to pick up
small objects from the floor

Getting out of a chair icon.

Getting out of a chair
without needing support

Climbing steps icon.

Climbing 12-15 steps
without using a handrail

Clock face icon.

Doing a full day of activities
at home or work

A woman fishing with a boy.

RINVOQ is approved for adults with active ankylosing spondylitis (AS) in whom TNF blockers did not work well.

What that
means for

If you're not getting relief from your AS symptoms, it may be time to rethink your treatment plan. Ask about RINVOQ


What best describes the status of your AS?

Pick one

Diagnosed and taking an NSAID (like aspirin or ibuprofen)

It may be time to talk to your rheumatologist about whether your current treatment is helping you get relief. Use a customized checklist to help you prepare for the conversation.

Start the Appointment Checklist

Diagnosed and on a biologic (injection or infusion) or oral small molecule

Prepare to talk treatment options and goals at your next rheumatologist visit—and ask about RINVOQ.

Start the Appointment Checklist

Not diagnosed

It’s time to get honest about your symptoms with a rheumatologist—a doctor who specializes in diseases like AS.

Partner with a rheumatologist

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Get more info and resources to jump-start your mission toward RINVOQ relief.