RINVOQ

For adults with active ankylosing spondylitis (AS) in whom TNF blockers did not work well.

In a clinical study, RINVOQ helped achieve

In a clinical study,
RINVOQ helped
achieve

Powerful relief.Powerful relief.

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RINVOQ helped many people significantly relieve their AS symptoms in 14 weeks vs placebo (44.5% vs. 18.2%). Some saw improvement as fast as 4 weeks.

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RINVOQ helped reduce overall AS disease activity, which was measured using a questionnaire about a range of symptoms, such as: joint pain and swelling, enthesitis (pain and swelling in areas like the heel and elbow), and morning stiffness.

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Improve AS quality of life for patients.

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RINVOQ may reduce AS fatigue.

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RINVOQ helped many people significantly relieve their AS symptoms in 14 weeks vs placebo (44.5% vs. 18.2%). Some saw improvement as fast as 4 weeks.

AS patients can experience an improved quality of life.

RINVOQ helped reduce overall AS disease activity, which was measured using a questionnaire about a range of symptoms, such as: joint pain and swelling, enthesitis (pain and swelling in areas like the heel and elbow), and morning stiffness.

RINVOQ may reduce AS fatigue.

Safety Considerations

RINVOQ may cause serious side effects, including:

  • Serious infections. RINVOQ can lower ability to fight infections. Serious infections, some fatal, occurred, including tuberculosis (TB) and infections caused by bacteria, fungi, or viruses.
  • Increased risk of death in people age 50+ with at least 1 heart disease risk factor.
  • Cancer and immune system problems. Increased risk of some cancers, including lymphoma and skin. Current or past smokers have higher risk for lymphoma and lung cancer.
  • Increased risk of major cardiovascular events such as heart attack, stroke, or death in people 50+ with at least 1 heart disease risk factor, especially in current or past smokers.
  • Blood clots, some fatal, in veins of the legs or lungs and arteries. This occurred more often in people 50+ with at least 1 heart disease risk factor.
  • Serious allergic reactions. Do not take if allergic to RINVOQ or its ingredients.
  • Tears in the stomach or intestines; changes in certain laboratory test results.

Learn more about these and the full Important Safety Information below.

Fast relief that can last

RINVOQ helped some people see an improvement in AS symptoms as fast as 4 weeks. Many people achieved significant relief from AS symptoms in 14 weeks.

Relief at 1 year (52 weeks)*

Of those who continued on RINVOQ for 1 year, many saw improvement in AS symptoms.

In a less rigorous part of the study, patients and physicians were aware of RINVOQ treatment, which may have influenced the results at 1 year.

Individual results may vary

*40% improvement in AS symptoms when used with or without csDMARDs, NSAIDs, or oral corticosteroids.

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Understanding the possible side effects of RINVOQ

Consider the benefits and risks of taking RINVOQ to make an informed treatment choice with your rheumatologist.

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Increased physical function

RINVOQ helped make it easier to do everyday tasks. People on RINVOQ completed a questionnaire that asked about their ability to perform activities, such as:

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Bending at the waist to pick up small objects from the floor

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Getting out of a chair without needing support

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Climbing 12-15 steps without using a handrail

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Doing a full day of activities at home or work

What that means for

If you’re not getting symptom relief, it may be time to rethink your treatment plan. Ask about RINVOQ at your next rheumatologist visit.

QUESTION FOR YOU

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What best describes the status of your AS?

Pick one

Diagnosed and taking an NSAID (like aspirin or ibuprofen)

It may be time to talk to your rheumatologist about whether your current treatment is helping you get relief. Use a customized checklist to help you prepare for the conversation.

Start the Appointment Checklist

Diagnosed and on a biologic (injection or infusion) or oral small molecule

If ankylosing spondylitis (AS) symptoms are getting in the way of what’s meaningful to you, it’s time to talk to your rheumatologist about making a change.

Learn to set treatment goals

Not diagnosed

It’s time to get honest about your symptoms with a rheumatologist—a doctor who specializes in diseases like AS.

Partner with a rheumatologist

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Taking RINVOQ