[Music under throughout]

TEXT ON SCREEN:

Here are some quick tips for giving your child RINVOQ LQ.

Please refer to the Instructions for Use, included with your child’s medicine, as your main resource for administering RINVOQ LQ.

Please see Important Safety Information near the end of this video.

Please see link for the full Prescribing Information, including the Medication Guide, and discuss with your child’s doctor.

ANNOUNCER VOICE-OVER:

Here are some quick tips for giving your child RINVOQ LQ.

Please refer to the Instructions for Use, included with your child’s medicine, as your main resource for administering RINVOQ LQ.

Please see Important Safety Information near the end of this video.

Please see link for the full Prescribing Information, including the Medication Guide, and discuss with your child’s doctor.

TEXT ON SCREEN:

USES
RINVOQ/RINVOQ LQ is a prescription medicine used to treat:

• Children 2 years of age and older with active polyarticular juvenile idiopathic arthritis (pJIA) when 1 or more medicines called tumor necrosis factor (TNF) blockers have been used, and did not work well or could not be tolerated.
• Children 2 to less than 18 years of age with active psoriatic arthritis (PsA) when 1 or more medicines called TNF blockers have been used, and did not work well or could not be tolerated.

It is not known if RINVOQ/RINVOQ LQ is safe and effective in children under 2 years of age with polyarticular juvenile idiopathic arthritis or psoriatic arthritis.

ANNOUNCER VOICE-OVER:

USES

RINVOQ/RINVOQ LQ is a prescription medicine used to treat:

Children 2 years of age and older with active polyarticular juvenile idiopathic arthritis (pJIA) when 1 or more medicines called tumor necrosis factor (TNF) blockers have been used, and did not work well or could not be tolerated.

Children 2 to less than 18 years of age with active psoriatic arthritis (PsA) when 1 or more medicines called TNF blockers have been used, and did not work well or could not be tolerated.

It is not known if RINVOQ/RINVOQ LQ is safe and effective in children under 2 years of age with polyarticular juvenile idiopathic arthritis or psoriatic arthritis.

TEXT ON SCREEN:

Safety Considerations for RINVOQ/RINVOQ LQ (upadacitinib)
RINVOQ* may cause serious side effects, including:

• Serious infections. RINVOQ can lower ability to fight infections. Serious infections, some fatal, occurred, including tuberculosis (TB) and infections caused by bacteria, fungi, or viruses.
• Increased risk of death in people age 50+ with at least 1 heart disease risk factor.
  
• Cancer and immune system problems. Increased risk of some cancers, including lymphoma and skin. Current or past smokers have higher risk for lymphoma and lung cancer.
• Increased risk of major cardiovascular events such as heart attack, stroke, or death in people 50+ with at least 1 heart disease risk factor, especially in current or past smokers.
• Blood clots, some fatal, in veins of the legs or lungs and arteries. This occurred more often in people 50+ with at least 1 heart disease risk factor.
• Serious allergic reactions. Do not take if allergic to RINVOQ or its ingredients.
• Tears in the stomach or intestines; changes in certain laboratory test results.

*Unless otherwise stated, “RINVOQ” in the Safety Considerations refers to RINVOQ and RINVOQ LQ.

ANNOUNCER VOICE-OVER:

Safety Considerations for RINVOQ/RINVOQ LQ (upadacitinib)

RINVOQ* may cause serious side effects, including:

Serious infections. RINVOQ can lower ability to fight infections. Serious infections, some fatal, occurred, including tuberculosis (TB) and infections caused by bacteria, fungi, or viruses.

Increased risk of death in people age 50+ with at least 1 heart disease risk factor.
Cancer and immune system problems. Increased risk of some cancers, including lymphoma and skin. Current or past smokers have higher risk for lymphoma and lung cancer.

Increased risk of major cardiovascular events, such as heart attack, stroke, or death in people 50+ with at least 1 heart disease risk factor, especially in current or past smokers.

Blood clots, some fatal, in veins of the legs or lungs and arteries. This occurred more often in people 50+ with at least 1 heart disease risk factor.

Serious allergic reactions. Do not take if allergic to RINVOQ or its ingredients

Tears in the stomach or intestines; changes in certain laboratory test results.

*Unless otherwise stated, “RINVOQ” in the Safety Considerations refers to RINVOQ and RINVOQ LQ.

TEXT ON SCREEN:

Giving RINVOQ LQ
Building a routine
Getting support

ANNOUNCER VOICE-OVER:

Starting your child on RINVOQ LQ can be a step forward.

You’ll want to know the right way to give your child RINVOQ LQ, how to build a routine, and where to get support.

Let’s walk through it now, so that you, and your child, can feel prepared.

TEXT ON SCREEN:

Giving your child RINVOQ LQ

Always give your child RINVOQ LQ exactly as prescribed by your child’s doctor.

ANNOUNCER VOICE-OVER:

Giving your child RINVOQ LQ.

TEXT ON SCREEN:

X2

Taken orally twice daily, with or without food.

Avoid food or drink containing grapefruit during treatment.

ANNOUNCER VOICE-OVER:

RINVOQ LQ is taken orally, twice daily, with or without food.

Avoid food or drink containing grapefruit during treatment.

TEXT ON SCREEN:

If the oral dosing syringe or press-in bottle adapter is lost or broken, call 1.800.2RINVOQ (1.800.274.6867).

ANNOUNCER VOICE-OVER:

Each carton of RINVOQ LQ comes with…

TEXT ON SCREEN:

BOTTLE
ORAL DOSING SYRINGE
PRESS-IN BOTTLE ADAPTER

Store RINVOQ LQ out of child’s reach at 36ºF to 86ºF (2ºC to 30ºC) in the original bottle.

ANNOUNCER VOICE-OVER:

…a bottle, a press-in bottle adapter, and a reusable oral dosing syringe.

TEXT ON SCREEN:

Do not remove adapter after it is inserted.

ANNOUNCER VOICE-OVER:

Before using a bottle of RINVOQ LQ for the first time, insert the adapter.

TEXT ON SCREEN:

FILL
Fill the syringe by inserting it into the press-in bottle adapter.

ANNOUNCER VOICE-OVER:

To give your child RINVOQ LQ, fill the syringe by inserting it into the press-in bottle adapter.

TEXT ON SCREEN:

Ask your child’s doctor to show you how to measure the prescribed dose.

ANNOUNCER VOICE-OVER:

Next, draw the solution into the syringe.

TEXT ON SCREEN:

You may feel pressure when pulling the plunger.

ANNOUNCER VOICE-OVER:

Check the syringe and remove any large air bubbles. See Instructions for Use for complete steps.

TEXT ON SCREEN:

REMOVE
Remove the syringe from the bottle.

ANNOUNCER VOICE-OVER:

Remove the syringe from the bottle.

TEXT ON SCREEN:

ADMINISTER
Administer the dose.

If your child is unable to swallow the full dose, call your child’s doctor.

ANNOUNCER VOICE-OVER:

Next, administer the dose.

TEXT ON SCREEN:

If your child is unable to swallow the full dose, call your child’s doctor.

ANNOUNCER VOICE-OVER:

Give RINVOQ LQ oral solution to your child by placing the syringe against the inside of your child’s cheek…

TEXT ON SCREEN:

RINVOQ LQ must be given within 1 hour of filling the syringe.

ANNOUNCER VOICE-OVER:

…until all the medication is dispensed. Then give your child a drink of water.

TEXT ON SCREEN:

RINSE
Rinse the syringe and plunger with water and air dry.

Do not use soap or put the syringe in the dishwasher to clean it. Allow the separated parts to air dry on a clean surface. Store the syringe in a clean, dry place.

ANNOUNCER VOICE-OVER:

When finished, rinse the syringe and plunger with water and air-dry.
It’s a twice-daily routine that you and your child can follow.

TEXT ON SCREEN:

Building a daily routine

ANNOUNCER VOICE-OVER:

Building a daily routine.

TEXT ON SCREEN:

[On phone]

Welcome!
Get started
Log in

ANNOUNCER VOICE-OVER:

Use the RINVOQ Complete App…

TEXT ON SCREEN:

SET MEDICATION REMINDERS AND TRACK DOSES

ANNOUNCER VOICE-OVER:

…to set medication reminders and track doses.

TEXT ON SCREEN:

Getting support

ANNOUNCER VOICE-OVER:

Getting support.
If you ever have any questions, reach out to your child’s doctor for answers.

TEXT ON SCREEN:

QUESTIONS?
Call your RINVOQ Complete Ambassador*
1.800.2RINVOQ (1.800.274.6867)

[On phone]

Anne
Your RINVOQ Complete Ambassador
1.800.2RINVOQ

*Nurse Ambassadors are provided by AbbVie and do not work under the direction of your health care professional (HCP) or give medical advice. They are trained to direct patients to their HCP for treatment-related advice, including further referrals.

ANNOUNCER VOICE-OVER:

You can also talk to your RINVOQ Complete Ambassador about building your routine and about giving your child RINVOQ LQ.

TEXT ON SCREEN:

24/7 LIVE CHAT

ANNOUNCER VOICE-OVER:

You can even get answers in the App, using Live Chat.
Remember, as you and your child take the next step with RINVOQ LQ, you can count on the support and resources of RINVOQ Complete.

TEXT ON SCREEN:

[RINVOQ/RINVOQ LQ Logo]
[RINVOQ Complete Logo]

Questions?
Call your RINVOQ Complete Ambassador
1.800.2RINVOQ (1.800.274.6867)

TEXT ON SCREEN:

IMPORTANT SAFETY INFORMATION FOR RINVOQ/RINVOQ LQ (upadacitinib)

What is the most important information I should know about RINVOQ*?

RINVOQ may cause serious side effects, including:

• Serious infections. RINVOQ can lower your ability to fight infections. Serious infections have happened while taking RINVOQ, including tuberculosis (TB) and infections caused by bacteria, fungi, or viruses that can spread throughout the body. Some people have died from these infections. Your healthcare provider (HCP) should test you for TB before starting RINVOQ and check you closely for signs and symptoms of TB during treatment with RINVOQ. You should not start taking RINVOQ if you have any kind of infection unless your HCP tells you it is okay. If you get a serious infection, your HCP may stop your treatment until your infection is controlled. You may be at higher risk of developing shingles (herpes zoster).

ANNOUNCER VOICE-OVER:

IMPORTANT SAFETY INFORMATION FOR RINVOQ/RINVOQ LQ (upadacitinib)

What is the most important information I should know about RINVOQ*?

RINVOQ may cause serious side effects, including:

Serious infections. RINVOQ can lower your ability to fight infections. Serious infections have happened while taking RINVOQ, including tuberculosis (TB) and infections caused by bacteria, fungi, or viruses that can spread throughout the body. Some people have died from these infections. Your healthcare provider (HCP) should test you for TB before starting RINVOQ and check you closely for signs and symptoms of TB during treatment with RINVOQ. You should not start taking RINVOQ if you have any kind of infection unless your HCP tells you it is okay. If you get a serious infection, your HCP may stop your treatment until your infection is controlled. You may be at higher risk of developing shingles (herpes zoster).

TEXT ON SCREEN:

• Increased risk of death in people 50 years and older who have at least 1 heart disease (cardiovascular) risk factor.
• Cancer and immune system problems. RINVOQ may increase your risk of certain cancers. Lymphoma and other cancers, including skin cancers, can happen. Current or past smokers are at higher risk of certain cancers, including lymphoma and lung cancer. Follow your HCP's advice about having your skin checked for skin cancer during treatment with RINVOQ. Limit the amount of time you spend in sunlight. Wear protective clothing when you are in the sun and use sunscreen.
• Increased risk of major cardiovascular (CV) events, such as heart attack, stroke, or death, in people 50 years and older who have at least 1 heart disease (CV) risk factor, especially if you are a current or past smoker.

ANNOUNCER VOICE-OVER:

Increased risk of death in people 50 years and older who have at least 1 heart disease (cardiovascular) risk factor.

Cancer and immune system problems. RINVOQ may increase your risk of certain cancers. Lymphoma and other cancers, including skin cancers, can happen. Current or past smokers are at higher risk of certain cancers, including lymphoma and lung cancer. Follow your HCP's advice about having your skin checked for skin cancer during treatment with RINVOQ. Limit the amount of time you spend in sunlight. Wear protective clothing when you are in the sun and use sunscreen.

Increased risk of major cardiovascular (CV) events, such as heart attack, stroke, or death, in people 50 years and older who have at least 1 heart disease (CV) risk factor, especially if you are a current or past smoker.

TEXT ON SCREEN:

• Blood clots. Blood clots in the veins of the legs or lungs and arteries can happen with RINVOQ. This may be life-threatening and cause death. Blood clots in the veins of the legs and lungs have happened more often in people who are 50 years and older and with at least 1 heart disease (CV) risk factor.
• Allergic reactions. Symptoms such as rash (hives), trouble breathing, feeling faint or dizzy, or swelling of your lips, tongue, or throat, that may mean you are having an allergic reaction have been seen in people taking RINVOQ. Some of these reactions were serious. If any of these symptoms occur during treatment with RINVOQ, stop taking RINVOQ and get emergency medical help right away.
• Tears in the stomach or intestines. This happens most often in people who take nonsteroidal anti-inflammatory drugs (NSAIDs) or corticosteroids. Get medical help right away if you get stomach-area pain, fever, chills, nausea, or vomiting.

ANNOUNCER VOICE-OVER:

Blood clots. Blood clots in the veins of the legs or lungs and arteries can happen with RINVOQ. This may be life-threatening and cause death. Blood clots in the veins of the legs and lungs have happened more often in people who are 50 years and older and with at least 1 heart disease (CV) risk factor.

Allergic reactions. Symptoms such as rash (hives), trouble breathing, feeling faint or dizzy, or swelling of your lips, tongue, or throat, that may mean you are having an allergic reaction have been seen in people taking RINVOQ. Some of these reactions were serious. If any of these symptoms occur during treatment with RINVOQ, stop taking RINVOQ and get emergency medical help right away.

Tears in the stomach or intestines. This happens most often in people who take nonsteroidal anti-inflammatory drugs (NSAIDs) or corticosteroids. Get medical help right away if you get stomach-area pain, fever, chills, nausea, or vomiting.

TEXT ON SCREEN:

• Changes in certain laboratory tests. Your HCP should do blood tests before you start taking RINVOQ and while you take it. Your HCP may stop your RINVOQ treatment for a period of time if needed because of changes in these blood test results.

Do not take RINVOQ if you are allergic to upadacitinib or any of the ingredients in RINVOQ. See the Medication Guide or Consumer Brief Summary for a complete list of ingredients.

What should I tell my HCP BEFORE starting RINVOQ?

Tell your HCP if you:

• Are being treated for an infection, have an infection that won't go away or keeps coming back, or have symptoms of an infection, such as:
  - Fever, sweating, or chills
  - Shortness of breath
  - Warm, red, or painful skin or sores on your body
  - Muscle aches
  - Feeling tired
  - Blood in phlegm
  - Diarrhea or stomach pain
  - Cough
  - Weight loss
  - Burning when urinating or urinating more often than normal

ANNOUNCER VOICE-OVER:

Changes in certain laboratory tests. Your HCP should do blood tests before you start taking RINVOQ and while you take it. Your HCP may stop your RINVOQ treatment for a period of time if needed because of changes in these blood test results.

Do not take RINVOQ if you are allergic to upadacitinib or any of the ingredients in RINVOQ. See the Medication Guide or Consumer Brief Summary for a complete list of ingredients.

What should I tell my HCP BEFORE starting RINVOQ?

Tell your HCP if you:

Are being treated for an infection, have an infection that won't go away or keeps coming back, or have symptoms of an infection, such as:

- Fever, sweating, or chills

- Shortness of breath

- Warm, red, or painful skin or sores on your body

- Muscle aches

- Feeling tired

- Blood in phlegm

- Diarrhea or stomach pain

- Cough

- Weight loss

- Burning when urinating or urinating more often than normal

TEXT ON SCREEN:

• Have TB or have been in close contact with someone with TB.
• Are a current or past smoker.
• Have had a heart attack, other heart problems, or stroke.
• Have or have had any type of cancer, hepatitis B or C, shingles (herpes zoster), blood clots in the veins of your legs or lungs, diverticulitis (inflammation in parts of the large intestine), or ulcers in your stomach or intestines.
• Have other medical conditions, including liver problems, low blood cell counts, diabetes, chronic lung disease, HIV, or a weak immune system.
• Live, have lived, or have traveled to parts of the country, such as the Ohio and Mississippi River valleys and the Southwest, that increase your risk of getting certain kinds of fungal infections. If you are unsure if you've been to these types of areas, ask your HCP.

ANNOUNCER VOICE-OVER:

Have TB or have been in close contact with someone with TB.

Are a current or past smoker.

Have had a heart attack, other heart problems, or stroke.

Have or have had any type of cancer, hepatitis B or C, shingles (herpes zoster), blood clots in the veins of your legs or lungs, diverticulitis (inflammation in parts of the large intestine), or ulcers in your stomach or intestines.

Have other medical conditions, including liver problems, low blood cell counts, diabetes, chronic lung disease, HIV, or a weak immune system.

Live, have lived, or have traveled to parts of the country, such as the Ohio and Mississippi River valleys and the Southwest, that increase your risk of getting certain kinds of fungal infections. If you are unsure if you've been to these types of areas, ask your HCP.

TEXT ON SCREEN:

• Have recently received or are scheduled to receive a vaccine. People who take RINVOQ should not receive live vaccines.
• Are pregnant or plan to become pregnant. Based on animal studies, RINVOQ may harm your unborn baby. Your HCP will check whether or not you are pregnant before you start RINVOQ. You should use effective birth control (contraception) to avoid becoming pregnant during treatment with RINVOQ and for 4 weeks after your last dose.
• There is a pregnancy surveillance program for RINVOQ. The purpose of the program is to collect information about the health of you and your baby. If you become pregnant while taking RINVOQ, you are encouraged to report the pregnancy by calling 1-800-633-9110.
• Are breastfeeding or plan to breastfeed. RINVOQ may pass into your breast milk. Do not breastfeed during treatment with RINVOQ and for 6 days after your last dose.

ANNOUNCER VOICE-OVER:

Have recently received or are scheduled to receive a vaccine. People who take RINVOQ should not receive live vaccines.

Are pregnant or plan to become pregnant. Based on animal studies, RINVOQ may harm your unborn baby. Your HCP will check whether or not you are pregnant before you start RINVOQ. You should use effective birth control (contraception) to avoid becoming pregnant during treatment with RINVOQ and for 4 weeks after your last dose.

There is a pregnancy surveillance program for RINVOQ. The purpose of the program is to collect information about the health of you and your baby. If you become pregnant while taking RINVOQ, you are encouraged to report the pregnancy by calling 1-800-633-9110.

Are breastfeeding or plan to breastfeed. RINVOQ may pass into your breast milk. Do not breastfeed during treatment with RINVOQ and for 6 days after your last dose.

TEXT ON SCREEN:

Tell your HCP about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. RINVOQ and other medicines may affect each other, causing side effects.

Especially tell your HCP if you take:

• Medicines for fungal or bacterial infections
• Rifampicin or phenytoin
• Medicines that affect your immune system

If you are not sure if you are taking any of these medicines, ask your HCP or pharmacist.

What should I avoid while taking RINVOQ?

Avoid food or drink containing grapefruit during treatment with RINVOQ as it may increase the risk of side effects.

ANNOUNCER VOICE-OVER:

Tell your HCP about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. RINVOQ and other medicines may affect each other, causing side effects.

Especially tell your HCP if you take:

Medicines for fungal or bacterial infections

Rifampicin or phenytoin

Medicines that affect your immune system

If you are not sure if you are taking any of these medicines, ask your HCP or pharmacist.

What should I avoid while taking RINVOQ?

Avoid food or drink containing grapefruit during treatment with RINVOQ as it may increase the risk of side effects.

TEXT ON SCREEN:

What should I do or tell my HCP AFTER starting RINVOQ?

• Tell your HCP right away if you have any symptoms of an infection. RINVOQ can make you more likely to get infections or make any infections you have worse.
• Get emergency help right away if you have any symptoms of a heart attack or stroke while taking RINVOQ, including:
  - Discomfort in the center of your chest that lasts for more than a few minutes or that goes away and comes back
  - Severe tightness, pain, pressure, or heaviness in your chest, throat, neck, or jaw
  - Pain or discomfort in your arms, back, neck, jaw, or stomach
  - Shortness of breath with or without chest discomfort
  - Breaking out in a cold sweat
  - Nausea or vomiting
  - Feeling lightheaded
  - Weakness in one part or on one side of your body
  - Slurred speech

ANNOUNCER VOICE-OVER:

What should I do or tell my HCP AFTER starting RINVOQ?

Tell your HCP right away if you have any symptoms of an infection. RINVOQ can make you more likely to get infections or make any infections you have worse.

Get emergency help right away if you have any symptoms of a heart attack or stroke while taking RINVOQ, including:

- Discomfort in the center of your chest that lasts for more than a few minutes or that goes away and comes back

- Severe tightness, pain, pressure, or heaviness in your chest, throat, neck, or jaw

- Pain or discomfort in your arms, back, neck, jaw, or stomach

- Shortness of breath with or without chest discomfort

- Breaking out in a cold sweat

- Nausea or vomiting

- Feeling lightheaded

- Weakness in one part or on one side of your body

- Slurred speech

TEXT ON SCREEN:

• Tell your HCP right away if you have any signs or symptoms of blood clots during treatment with RINVOQ, including:
  - Swelling
  - Pain or tenderness in one or both legs
  - Sudden unexplained chest or upper back pain
  - Shortness of breath or difficulty breathing
• Tell your HCP right away if you have a fever or stomach-area pain that does not go away, and a change in your bowel habits.

What are other possible side effects of RINVOQ?

Common side effects include upper respiratory tract infections (common cold, sinus infections), shingles (herpes zoster), herpes simplex virus infections (including cold sores), bronchitis, nausea, cough, fever, acne, headache, swelling of the feet and hands (peripheral edema), increased blood levels of creatine phosphokinase, allergic reactions, inflammation of hair follicles, stomach-area (abdominal) pain, increased weight, flu, tiredness, lower number of certain types of white blood cells (neutropenia, lymphopenia, leukopenia), muscle pain, flu-like illness, rash, increased blood cholesterol levels, increased liver enzyme levels, pneumonia, low number of red blood cells (anemia), and infection of the stomach and intestine (gastroenteritis).

ANNOUNCER VOICE-OVER:

Tell your HCP right away if you have any signs or symptoms of blood clots during treatment with RINVOQ, including:

- Swelling

- Pain or tenderness in one or both legs

- Sudden unexplained chest or upper back pain

- Shortness of breath or difficulty breathing

Tell your HCP right away if you have a fever or stomach-area pain that does not go away, and a change in your bowel habits.

What are other possible side effects of RINVOQ?

Common side effects include upper respiratory tract infections (common cold, sinus infections), shingles (herpes zoster), herpes simplex virus infections (including cold sores), bronchitis, nausea, cough, fever, acne, headache, swelling of the feet and hands (peripheral edema), increased blood levels of creatine phosphokinase, allergic reactions, inflammation of hair follicles, stomach-area (abdominal) pain, increased weight, flu, tiredness, lower number of certain types of white blood cells (neutropenia, lymphopenia, leukopenia), muscle pain, flu-like illness, rash, increased blood cholesterol levels, increased liver enzyme levels, pneumonia, low number of red blood cells (anemia), and infection of the stomach and intestine (gastroenteritis).

TEXT ON SCREEN:

A separation or tear to the lining of the back part of the eye (retinal detachment) has happened in people with atopic dermatitis treated with RINVOQ. Call your HCP right away if you have any sudden changes in your vision during treatment with RINVOQ.

Some people taking RINVOQ may see medicine residue (a whole tablet or tablet pieces) in their stool. If this happens, call your HCP.

These are not all the possible side effects of RINVOQ.

How should I take RINVOQ/RINVOQ LQ?

RINVOQ is taken once a day with or without food. Do not split, crush, or chew the tablet. Take RINVOQ exactly as your HCP tells you to use it. RINVOQ is available in 15 mg, 30 mg, and 45 mg extended-release tablets. RINVOQ LQ is taken twice a day with or without food. RINVOQ LQ is available in a 1 mg/mL oral solution. RINVOQ LQ is not the same as RINVOQ tablets. Do not switch between RINVOQ LQ and RINVOQ tablets unless the change has been made by your HCP.

ANNOUNCER VOICE-OVER:

A separation or tear to the lining of the back part of the eye (retinal detachment) has happened in people with atopic dermatitis treated with RINVOQ. Call your HCP right away if you have any sudden changes in your vision during treatment with RINVOQ.

Some people taking RINVOQ may see medicine residue (a whole tablet or tablet pieces) in their stool. If this happens, call your HCP.

These are not all the possible side effects of RINVOQ.

How should I take RINVOQ/RINVOQ LQ?

RINVOQ is taken once a day with or without food. Do not split, crush, or chew the tablet. Take RINVOQ exactly as your HCP tells you to use it. RINVOQ is available in 15 mg, 30 mg, and 45 mg extended-release tablets. RINVOQ LQ is taken twice a day with or without food. RINVOQ LQ is available in a 1 mg/mL oral solution. RINVOQ LQ is not the same as RINVOQ tablets. Do not switch between RINVOQ LQ and RINVOQ tablets unless the change has been made by your HCP.

TEXT ON SCREEN:

*Unless otherwise stated, "RINVOQ" in the IMPORTANT SAFETY INFORMATION refers to RINVOQ and RINVOQ LQ.

This is the most important information to know about RINVOQ. For more information, talk to your HCP.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

If you are having difficulty paying for your medicine, AbbVie may be able to help. Visit AbbVie.com/PatientAccessSupport to learn more.

Please see link for the full Prescribing Information, including the Medication Guide, and discuss with your child's doctor.

US-RNQR-240136

© 2025 AbbVie. All rights reserved. RINVOQ and its design are trademarks of AbbVie Biotechnology Ltd.

ANNOUNCER VOICE-OVER:

*Unless otherwise stated, "RINVOQ" in the IMPORTANT SAFETY INFORMATION refers to RINVOQ and RINVOQ LQ.

This is the most important information to know about RINVOQ. For more information, talk to your HCP.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

If you are having difficulty paying for your medicine, AbbVie may be able to help. Visit AbbVie.com/PatientAccessSupport to learn more.

Please see link for the full Prescribing Information, including the Medication Guide, and discuss with your child's doctor.