WITH ACTIVE PSORIATIC ARTHRITIS
WITH ACTIVE PSORIATIC
ARTHRITIS
For adults with active psoriatic arthritis (PsA) in whom TNF blockers did not work well.
About active psoriatic arthritis (PsA)
PsA is a chronic (ongoing) condition. This means symptoms may keep coming back and last a long time. It can cause inflammation of the joints and tissues around the joints. It can also limit your ability to do simple, everyday activities.
Front of body
What is inflammation?
Normally, the immune system protects your body from disease by attacking bacteria and viruses. But with PsA, the immune system malfunctions and attacks your own body's healthy tissues, specifically the joints.
Inflammation is your body's normal response to protect against something your immune system thinks will cause harm. When excess inflammation caused by your immune system doesn't go away, it can lead to conditions like PsA.
How the immune system triggers inflammation
When you are living with PsA, the inflammation does not go away over time. This can lead to the following PsA symptoms:
- Joint pain, swelling, and stiffness
- Irreversible joint damage
- Skin plaques
- Fatigue
Helpful tips for managing PsA
Here are some steps you can take to help you manage your PsA symptoms.
Taking RINVOQ
It’s important to remember that PsA is a chronic, or ongoing, condition. Taking RINVOQ as prescribed is important as PsA can persist even though you don’t have symptoms.
RINVOQ must be taken exactly as prescribed by your doctor
- Take RINVOQ once a day, every day
- RINVOQ can be taken with or without food. Avoid food or drink containing grapefruit
- Do not split, crush, or chew the pill
Call your healthcare provider if you see medication residue (a whole tablet or tablet pieces) in your stool.
What should you do if you miss a dose?
- Call the doctor about the missed dose
- Set up a visual cue or reminder that will help you remember to take RINVOQ
- Use treatment reminders and fill out your treatment log in the RINVOQ Complete App, so you’ll know when/if you have taken RINVOQ
Check in with the doctor
Regular check-ins and open discussions with the doctor can help you stay on track with a prescribed treatment plan.
Track symptoms
Use the RINVOQ Complete App to keep track of symptoms and share them with your doctor.
How RINVOQ works
With PsA, your overactive immune system attacks your joints. RINVOQ helps regulate your overactive immune system to help stop the attack. RINVOQ works inside your cells to block certain signals that are thought to cause inflammation.
Because JAK inhibitors, including RINVOQ, affect the immune system, they can lower the ability to fight infections and may cause other serious side effects. It's important to talk to your healthcare provider about the possible side effects of prescription treatments.
Transcript
Music track throughout.
ANNOUNCER VOICE OVER (AVO): With psoriatic arthritis,
TEXT ON SCREEN: YOUR OVERACTIVE IMMUNE SYSTEM
AVO: …your overactive immune system…
TEXT ON SCREEN: ATTACKS JOINTS
AVO: …attacks joints…
TEXT ON SCREEN: AND ATTACKS SKIN
AVO: …and attacks skin–and may cause inflammation that contributes to symptoms throughout your body.
TEXT ON SCREEN: RINVOQ® (upadacitinib)
RINVOQ is a prescription medicine used to treat adults with active psoriatic arthritis (PsA) when 1 or more medicines called tumor necrosis factor (TNF) blockers have been used, and did not work well or could not be tolerated. It is not known if RINVOQ is safe and effective in children under 2 years of age with psoriatic arthritis.
Please see Important Safety Information in video and on this webpage. Please see link for the full Prescribing Information, including the Medication Guide.
AVO: That’s where RINVOQ can help. RINVOQ is a prescription medicine used to treat adults with active psoriatic arthritis in whom TNF blockers did not work well.
TEXT ON SCREEN: GET AN INSIDE LOOK AT HOW IT WORKS
AVO: Let’s take a deeper, inside look at how it works in your body.
TEXT ON SCREEN: For illustrative purposes only
AVO: RINVOQ is a JAK inhibitor that works inside your cells to block certain signals that are thought to cause inflammation.
TEXT ON SCREEN: RINVOQ® (upadacitinib)
RINVOQ is not approved to treat plaque psoriasis.
TEXT ON SCREEN: REGULATES & HELPS STOP
AVO: RINVOQ regulates your overactive immune system to help stop the attack.
TEXT ON SCREEN: RINVOQ HELPS RELIEVE PsA
JOINT SYMPTOMS
SKIN SYMPTOMS
FATIGUE
AVO: Clinical studies have proven RINVOQ helps relieve PsA joint symptoms, skin symptoms, and fatigue.
TEXT ON SCREEN: RINVOQ® (upadacitinib)
ASK YOUR RHEUMATOLOGIST ABOUT RINVOQ RELIEF
AVO: That’s RINVOQ Relief.
TEXT ON SCREEN: RINVOQ® (upadacitinib)
Safety Considerations
RINVOQ may cause serious side effects, including:
- Serious infections. RINVOQ can lower ability to fight infections. Serious infections, some fatal, occurred, including tuberculosis (TB) and infections caused by bacteria, fungi, or viruses.
- Increased risk of death in people age 50+ with at least 1 heart disease risk factor.
- Cancer and immune system problems. Increased risk of some cancers, including lymphoma and skin. Current or past smokers have higher risk for lymphoma and lung cancer.
- Increased risk of major cardiovascular events such as heart attack, stroke, or death in people 50+ with at least 1 heart disease risk factor, especially in current or past smokers.
- Blood clots, some fatal, in veins of the legs or lungs and arteries. This occurred more often in people 50+ with at least 1 heart disease risk factor.
- Serious allergic reactions. Do not take if allergic to RINVOQ or its ingredients.
- Tears in the stomach or intestines; changes in certain laboratory test results.
Please see additional Important Safety Information on this webpage.
AVO: Safety Considerations. RINVOQ may cause serious side effects, including:
- Serious infections. RINVOQ can lower ability to fight infections. Serious infections, some fatal, occurred, including tuberculosis (TB) and infections caused by bacteria, fungi, or viruses.
- Increased risk of death in people age 50+ with at least 1 heart disease risk factor.
- Cancer and immune system problems. Increased risk of some cancers, including lymphoma and skin. Current or past smokers have higher risk for lymphoma and lung cancer.
- Increased risk of major cardiovascular events such as heart attack, stroke, or death in people 50+ with at least 1 heart disease risk factor, especially in current or past smokers.
- Blood clots, some fatal, in veins of the legs or lungs and arteries. This occurred more often in people 50+ with at least 1 heart disease risk factor.
- Serious allergic reactions. Do not take if allergic to RINVOQ or its ingredients.
- Tears in the stomach or intestines; changes in certain laboratory test results.
Please see additional Important Safety Information on this webpage.
Select Important Safety Information
RINVOQ may cause serious side effects, including:
- Serious Infections, Cancer and Immune System Problems, and Blood Clots.
- Increased risk of death in people age 50+ with at least 1 heart disease risk factor.
- Increased risk of major cardiovascular events, such as heart attack, stroke, or death in people age 50+ with at least 1 heart disease risk factor, especially in current or past smokers.
- Serious allergic reactions. Do not take if allergic to RINVOQ or its ingredients.
See full Important Safety Information below.
Set reminders
Use the App to set medication reminders and track doses.
RINVOQ results
Proven in clinical studies, RINVOQ can:
- Significantly relieve joint pain, swelling, and stiffness for the majority of people at 12 weeks. For some, PsA symptoms improved as early as 2 weeks.
- Stop further irreversible joint damage
- Leave skin* noticeably clearer for people with PsA skin plaques
- Significantly reduce PsA fatigue
*RINVOQ is not approved to treat plaque psoriasis.
Understanding the possible side effects of RINVOQ
Always consider the benefits and risks of taking RINVOQ and discuss with your doctor.
Get 1-to-1 support from your RINVOQ Complete Nurse Ambassador†
Reach out when you need answers. Just call 1.800.2RINVOQ (1.800.274.6867).
†Nurse Ambassadors are provided by AbbVie and do not work under the direction of your health care professional (HCP) or give medical advice. They are trained to direct patients to their HCP for treatment-related advice, including further referrals.
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