WITH MODERATE TO SEVERE RHEUMATOID ARTHRITIS
WITH MODERATE TO SEVERE RHEUMATOID ARTHRITIS
For adults with moderate to severe rheumatoid arthritis (RA) in whom TNF blockers did not work well.
About rheumatoid arthritis (RA)
Rheumatoid arthritis (RA) is a persistent autoimmune disorder where the immune system mistakenly targets healthy cells, resulting in inflammation of the joints, particularly those in the hands, wrists, and knees. This inflammation can lead to joint pain, swelling, and stiffness, and if not addressed, may cause irreversible joint damage.
Front of body
What is inflammation?
In rheumatoid arthritis (RA), the immune system becomes excessively active and mistakenly sends white blood cells, along with other cells and proteins, to healthy joints, resulting in inflammation.
Typically, inflammation is your body's natural way of safeguarding against perceived threats. However, when inflammation persists due to the immune system's misguided response, it can lead to conditions such as RA.
How the immune system triggers inflammation
When you are living with RA, your overactive immune system causes inflammation that attacks the joints, which can lead to symptoms like:
- Joint pain, swelling, and stiffness
- Irreversible joint damage
- Fatigue
Taking RINVOQ
It’s important to remember that RA is a chronic, or ongoing, condition. Taking RINVOQ as prescribed is important as RA can last even though you don’t have symptoms.
RINVOQ must be taken exactly as prescribed by your doctor
- Take RINVOQ once a day, every day
- RINVOQ can be taken with or without food. Avoid food or drink containing grapefruit
- Do not split, crush, or chew the pill
Call your healthcare provider if you see medication residue (a whole tablet or tablet pieces) in your stool.
What should you do if you miss a dose?
- Call the doctor about the missed dose
- Set up a visual cue or reminder that will help you remember to take RINVOQ
- Use treatment reminders and fill out your treatment log in the RINVOQ Complete App, so you’ll know when/if you have taken RINVOQ
Check in with your doctor
Regular check-ins and open discussions with the doctor can help you stay on track with a prescribed treatment plan.
Track symptoms
Use the RINVOQ Complete App to keep track of symptoms and share them with your doctor.
How RINVOQ works
With RA, an overactive immune system may cause excess inflammation, contributing to symptoms like joint pain and stiffness. RINVOQ works inside your cells to block certain signals that are thought to cause inflammation.
Because JAK inhibitors, including RINVOQ, affect the immune system, they can lower the ability to fight infections and may cause other serious side effects. It's important to talk to your healthcare provider about the possible side effects of prescription treatments.
Transcript
Music track throughout.
ANNOUNCER VOICE OVER (AVO): With rheumatoid arthritis,…
TEXT ON SCREEN: YOUR OVERACTIVE IMMUNE SYSTEM
ANNOUNCER VOICE OVER (AVO): …your overactive immune system…
TEXT ON SCREEN: ATTACKS JOINTS
AVO: …attacks joints and may cause inflammation that contributes to
symptoms throughout your body.
TEXT ON SCREEN: RINVOQ® (upadacitinib)
RINVOQ is a prescription medicine used to treat adults with moderate to severe rheumatoid arthritis (RA) when 1 or more medicines called tumor necrosis factor (TNF) blockers have been used, and did not work well or could not be tolerated. It is not known if RINVOQ is safe and effective in children under 2 years of age with polyarticular juvenile idiopathic arthritis (pJIA).
Please see Important Safety Information in video and on this webpage.
Please see link for the full Prescribing Information, including the Medication Guide.
AVO: That’s where RINVOQ can help. RINVOQ is a prescription
medicine used to treat adults with moderate to severe rheumatoid
arthritis in whom TNF blockers did not work well.
TEXT ON SCREEN: GET AN INSIDE LOOK AT HOW IT WORKS
AVO: Let’s take a deeper, inside look at how it works in your body.
TEXT ON SCREEN: For illustrative purposes only
AVO: RINVOQ is a JAK inhibitor that works inside your cells to block
certain signals that are thought to cause inflammation.
TEXT ON SCREEN: RINVOQ® (upadacitinib)
REGULATES & HELPS STOP
AVO: RINVOQ regulates your overactive immune system to help stop
the attack.
TEXT ON SCREEN: RINVOQ HELPS REDUCE
PAIN
STIFFNESS
SWELLING
RA FATIGUE
AVO: Clinical studies have proven RINVOQ helps reduce pain,
stiffness, swelling, and for some it can even significantly reduce RA
fatigue.
TEXT ON SCREEN: RINVOQ® (upadacitinib)
ASK YOUR RHEUMATOLOGIST ABOUT RINVOQ RELIEF
AVO: That’s RINVOQ Relief.
TEXT ON SCREEN: RINVOQ® (upadacitinib)
Safety Considerations
RINVOQ may cause serious side effects, including:
- Serious infections. RINVOQ can lower ability to fight infections. Serious infections, some fatal, occurred, including tuberculosis (TB) and infections caused by bacteria, fungi, or viruses.
- Increased risk of death in people age 50+ with at least 1 heart disease risk factor.
- Cancer and immune system problems. Increased risk of some cancers, including lymphoma and skin. Current or past smokers have higher risk for lymphoma and lung cancer.
- Increased risk of major cardiovascular events such as heart attack, stroke, or death in people 50+ with at least 1 heart disease risk factor, especially in current or past smokers.
- Blood clots, some fatal, in veins of the legs or lungs and arteries. This occurred more often in people 50+ with at least 1 heart disease risk factor.
- Serious allergic reactions. Do not take if allergic to RINVOQ or its ingredients.
- Tears in the stomach or intestines; changes in certain laboratory test results.
Please see additional Important Safety Information on this webpage.
AVO: Safety Considerations. RINVOQ may cause serious side effects, including:
- Serious infections. RINVOQ can lower ability to fight infections. Serious infections, some fatal, occurred, including tuberculosis (TB) and infections caused by bacteria, fungi, or viruses.
- Increased risk of death in people age 50+ with at least 1 heart disease risk factor.
- Cancer and immune system problems. Increased risk of some cancers, including lymphoma and skin. Current or past smokers have higher risk for lymphoma and lung cancer.
- Increased risk of major cardiovascular events such as heart attack, stroke, or death in people 50+ with at least 1 heart disease risk factor, especially in current or past smokers.
- Blood clots, some fatal, in veins of the legs or lungs and arteries. This occurred more often in people 50+ with at least 1 heart disease risk factor.
- Serious allergic reactions. Do not take if allergic to RINVOQ or its ingredients.
- Tears in the stomach or intestines; changes in certain laboratory test results.
Please see additional Important Safety Information on this webpage.
Select Important Safety Information
RINVOQ may cause serious side effects, including:
- Serious Infections, Cancer and Immune System Problems, and Blood Clots.
- Increased risk of death in people age 50+ with at least 1 heart disease risk factor.
- Increased risk of major cardiovascular events, such as heart attack, stroke, or death in people age 50+ with at least 1 heart disease risk factor, especially in current or past smokers.
- Serious allergic reactions. Do not take if allergic to RINVOQ or its ingredients.
See full Important Safety Information below.
Set reminders
Use the App to set medication reminders and track doses.
Understanding the possible side effects of RINVOQ
Always consider the benefits and risks of taking RINVOQ and discuss with your doctor.
Get 1-to-1 support from your RINVOQ Complete Nurse Ambassador*
Reach out when you need answers. Just call 1.800.2RINVOQ (1.800.274.6867).
*Nurse Ambassadors are provided by AbbVie and do not work under the direction of your health care professional (HCP) or give medical advice. They are trained to direct patients to their HCP for treatment-related advice, including further referrals.
Build a routine with the RINVOQ Complete App
Use medication reminders and track your doses so you know when/if you’ve taken your medicine
Log and share symptoms with your doctor
Set personal goals to help you manage your condition, track your progress, and stay motivated
Download the App now
Search for “RINVOQ Complete” at the App Store® or Google Play™.
Text APP to 33101 to receive a link to download the RINVOQ Complete App
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