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Safety Considerations
RINVOQ may cause serious side effects, including:
Learn more about these and the full Important Safety Information below.
In a clinical study, RINVOQ helped relieve PsA joint pain, swelling, and stiffness for some people in as little as 2 weeks. The majority of people taking RINVOQ had significantly improved symptoms at 12 weeks.
A similar percentage of people reported relief over a year later (at 56 weeks).†
Individual results may vary.
Relief at 3 years (152 weeks†)
Of those who continued taking RINVOQ for 3 years, many saw improvement in PsA symptoms. In this less rigorous part of the study, patients and physicians were aware of RINVOQ treatment, which may have influenced these results at 3 years.
†20% improvement in PsA symptoms when used with or without csDMARDs. Doctors adjusted supportive PsA medicines as needed at week 16 or 36.
In a clinical trial, the majority of people achieved 75% skin* clearance at 4 months.
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RINVOQ has not been studied in and is not indicated for the treatment of plaque psoriasis.
Consider the benefits and risks of taking RINVOQ to make an informed treatment choice with your rheumatologist.
If you’re unsatisfied with your current treatment plan—talk to your rheumatologist about other treatment options to help get your PsA symptoms under control. Partner With a Rheumatologist >
A rheumatologist can evaluate your PsA symptoms and help create a treatment plan that meets your unique needs. Find a Rheumatologist >
Your response to treatment can change over time, so learning about PsA treatment options can help you make informed decisions with your rheumatologist.
If you're still having PsA symptoms, make a rheumatologist appointment as soon as possible and let them know how your symptoms are affecting you. They can help you treat your PsA and reach your treatment goals. Find a rheumatologist >
If you're still having PsA symptoms, make a rheumatologist appointment as soon as possible and let them know how your symptoms are affecting you. They can help you treat your PsA and reach your treatment goals. Find a rheumatologist >
RINVOQ helps fight PsA joint pain, swelling, stiffness, skin* symptoms, and PsA fatigue in a once-daily pill. But to see if RINVOQ can be a part of your treatment plan, you first have to ask your rheumatologist.
Share your experience with RINVOQ to help inform and inspire others. To participate, please email us at info@SPEAKnetwork.net or call 877-861-6180.
RINVOQ is a prescription medicine used to treat adults with active psoriatic arthritis when 1 or more medicines called tumor necrosis factor (TNF) blockers have been used, and did not work well or could not be tolerated. It is not known if RINVOQ is safe and effective in children with psoriatic arthritis.
IMPORTANT SAFETY INFORMATION
What is the most important information I should know about RINVOQ?
RINVOQ may cause serious side effects, including:
Do not take RINVOQ if you are allergic to upadacitinib or any of the ingredients in RINVOQ. See the Medication Guide or Consumer Brief Summary for a complete list of ingredients.
What should I tell my HCP BEFORE starting RINVOQ?
Tell your HCP if you:
Tell your HCP about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. RINVOQ and other medicines may affect each other, causing side effects.
Especially tell your HCP if you take:
If you are not sure if you are taking any of these medicines, ask your HCP or pharmacist.
What should I avoid while taking RINVOQ?
Avoid food or drink containing grapefruit during treatment with RINVOQ as it may increase the risk of side effects.
What should I do or tell my HCP AFTER starting RINVOQ?
What are other possible side effects of RINVOQ?
Common side effects include upper respiratory tract infections (common cold, sinus infections), shingles (herpes zoster), herpes simplex virus infections (including cold sores), bronchitis, nausea, cough, fever, acne, headache, increased blood levels of creatine phosphokinase, allergic reactions, inflammation of hair follicles, stomach-area (abdominal) pain, increased weight, flu, tiredness, lower number of certain types of white blood cells (neutropenia, lymphopenia, leukopenia), muscle pain, flu-like illness, rash, increased blood cholesterol levels, increased liver enzyme levels, pneumonia, low number of red blood cells (anemia), and infection of the stomach and intestine (gastroenteritis).
A separation or tear to the lining of the back part of the eye (retinal detachment) has happened in people with atopic dermatitis treated with RINVOQ. Call your HCP right away if you have any sudden changes in your vision during treatment with RINVOQ.
Some people taking RINVOQ may see medicine residue (a whole tablet or tablet pieces) in their stool. If this happens, call your healthcare provider.
These are not all the possible side effects of RINVOQ.
How should I take RINVOQ?
RINVOQ is taken once a day with or without food. Do not split, crush, or chew the tablet. Take RINVOQ exactly as your HCP tells you to use it. RINVOQ is available in 15 mg, 30 mg, and 45 mg extended-release tablets.
This is the most important information to know about RINVOQ. For more information, talk to your HCP.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.
USES
RINVOQ is a prescription medicine used to treat:
It is not known if RINVOQ is safe and effective in children with juvenile idiopathic arthritis, psoriatic arthritis, ankylosing spondylitis, non-radiographic axial spondyloarthritis, ulcerative colitis, or Crohn’s disease.
RINVOQ is safe and effective in children 12 years of age and older weighing at least 88 pounds (40 kg) with atopic dermatitis.
It is not known if RINVOQ is safe and effective in children under 12 years of age with atopic dermatitis.
If you are having difficulty paying for your medicine, AbbVie may be able to help. Visit AbbVie.com/myAbbVieAssist to learn more.
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Please see the Full Prescribing Information, including the Medication Guide, for RINVOQ.
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