What is ulcerative

Important facts about UC

UC belongs to a larger group of illnesses called inflammatory bowel diseases (IBD). UC is a chronic—ongoing, long-term—condition where inflammation in the large intestine (colon and rectum) can lead to symptoms over time. With UC, your overactive immune system causes inflammation that damages your colon lining. 

keep in mind

If you are still experiencing UC symptoms, there may still be inflammation in the intestines that can lead to colon lining damage. That's why it's important to team up with a gastroenterologist early on to find a treatment that may be right for you.

How UC occurs

Your immune system mistakenly harms healthy cells in the inner lining of the large intestine, or colon

The overactivity of the immune system causes excess inflammation in your colon

Too much inflammation can lead to colon damage and UC symptoms

The exact cause of UC is unknown, but it can be influenced by many different factors, including a person's immune system, genetics, or other environmental factors.

This inner layer is called the epithelial tissue, which is found throughout the body. It protects your body’s organs, as well as performs secretory, transport, and absorption functions

An organ in the digestive system that absorbs water and other elements from partially digested food to form stools that are passed out of the body. The colon is also known as the large intestine

Some common UC symptoms:

Sudden accidents

Abdominal pain

Frequent bathroom trips

Bloody stools


Your gastroenterologist may also use the term "urgency" to describe not being able to wait to use a bathroom

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Matt’s Story

I wasn’t in control of when and where I could go to the bathroom.

—MATT, moderate to severe UC patient


UC shouldn't take charge of your

The severity of your symptoms may be a sign of inflammation in your colon.


Learn how setting proactive treatment goals can help you go beyond temporary symptom relief and prioritize addressing damage caused by chronic inflammation.


If your UC symptoms are getting in the way of day-to-day activities, it may be time to talk to your gastroenterologist.

Understand the importance of setting proactive Goals for UC Treatment >

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Frequently asked questions about RINVOQ

Get answers to some of the most commonly asked questions about RINVOQ.

See RINVOQ in action

RINVOQ UC clinical study results won’t back down


should you.